BDBM142546 US8933224, 139

SMILES Cc1nc([C@@H]2CCOC2)c2c(ncnn12)N1CCc2nc(C)ccc2C1

InChI Key InChIKey=IKUXIHAPMKHTDP-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142546   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM142546(US8933224, 139)
Affinity DataIC50:  0.279nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Pfizer

US Patent
LigandPNGBDBM142546(US8933224, 139)
Affinity DataIC50:  0.270nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In DepthDetails US Patent