BDBM143179 US8940744, 4::US9266895, 4

SMILES CN1CCN(CC1)C(C)(C)C=C([N+]#[C-])C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12

InChI Key InChIKey=CCNPBGMGMDSPQW-HSZRJFAPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143179   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143179(US8940744, 4 | US9266895, 4)
Affinity DataIC50:  0.300nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143179(US8940744, 4 | US9266895, 4)
Affinity DataIC50:  0.300nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent