BDBM143187 US9682953, 2.A-14::US9682953, 2.A-15

SMILES Fc1ccc(cn1)C(=O)NC1CCC(CC1)=Cc1cccc(Oc2ccc(cn2)C(F)(F)F)c1

InChI Key InChIKey=LEMIKFJIMVYGDR-VBKFSLOCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 143187   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM143187(US9682953, 2.A-14 | US9682953, 2.A-15)
Affinity DataIC50:  10nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Advinus Therapeutics

US Patent
LigandPNGBDBM143187(US9682953, 2.A-14 | US9682953, 2.A-15)
Affinity DataIC50:  188nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Advinus Therapeutics

US Patent
LigandPNGBDBM143187(US9682953, 2.A-14 | US9682953, 2.A-15)
Affinity DataIC50:  5nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent