BDBM14329 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-methyl-6-phenylbenzen-1-olate::CRA-9075

SMILES Cc1cc(-c2cc3cc(ccc3[nH]2)C(N)=[NH2+])c([O-])c(c1)-c1ccccc1

InChI Key InChIKey=ALBWLRSLXFJFTE-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14329   

TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  15nM ΔG°:  -10.6kcal/molepH: 7.6 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  180nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  340nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  380nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14329(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-met...)
Affinity DataKi:  1.10E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed