BDBM14340 (2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-4-oxido-5-phenylphenyl)butanedioate::5-amidino benzimidazole analog 1::CRA-16935

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)-c1cc(cc(-c2ccccc2)c1[O-])[C@@H](CC([O-])=O)C([O-])=O

InChI Key InChIKey=FXLFNEVHWHPROF-MRXNPFEDSA-L

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14340   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  120nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  290nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.20E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  3.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14340((2R)-2-(3-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.60E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed