BDBM14347 CRA-1802::{amino[2-(5-fluoro-2-hydroxyphenyl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)-c1cc(F)ccc1O

InChI Key InChIKey=JOGOACSSLJEREC-UHFFFAOYSA-O

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14347   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14347(CRA-1802 | {amino[2-(5-fluoro-2-hydroxyphenyl)-1H-...)
Affinity DataKi:  6.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14347(CRA-1802 | {amino[2-(5-fluoro-2-hydroxyphenyl)-1H-...)
Affinity DataKi:  6.50E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14347(CRA-1802 | {amino[2-(5-fluoro-2-hydroxyphenyl)-1H-...)
Affinity DataKi:  1.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14347(CRA-1802 | {amino[2-(5-fluoro-2-hydroxyphenyl)-1H-...)
Affinity DataKi:  3.30E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed