BDBM143556 US9682955, 41

SMILES OCC(CO)(CO)NC(=O)c1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ncnc2ccc(cc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=RJOVFKSPARKKHK-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 143556   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM143556(US9682955, 41)
Affinity DataEC50:  8nMT: 2°CAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM143556(US9682955, 41)
Affinity DataEC50:  1.47E+3nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in HEK293 cells assessed as forskolin-stimulated cAMP accumulation after 30 mins by HTRF ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM143556(US9682955, 41)
Affinity DataEC50:  7.80nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells assessed as forskolin-stimulated cAMP accumulation after 30 mins by HTRF ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM143556(US9682955, 41)
Affinity DataEC50:  1.47E+3nMT: 2°CAssay Description:The following mixtures and buffer solutions were prepared: (a) Buffer 1: HBSS (Mediatech Cat#21-023-CV) with 5 mM HEPES (1 mM stock, Gibco BRL Cat#15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent