BDBM14374 (2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-{2-[(3,5-dimethoxyphenyl)methoxy]propan-2-yl}-3H-purin-6-amine::3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,5-dimethoxy-benzyloxy)-1-methyl-ethyl]-3Hpurin-6-ylamine Fumarate::V11294 Analogue 5j
SMILES COc1cc(COC(C)(C)c2nc3c(N)ncn(Cc4ccc(OC)c(OC5CCCC5)c4)c3n2)cc(OC)c1
InChI Key InChIKey=WKIZWUJJDQILGH-UHFFFAOYSA-N
Data 5 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 14374
Affinity DataKi: 7.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 21.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 225nM ΔG°: -8.97kcal/molepH: 8.0 T: 2°CAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair