BDBM144277 US8969333, YW3-56

SMILES CN(C)c1ccc2cc(ccc2c1)C(=O)N[C@@H](CCCNC(=N)CCl)C(=O)NCc1ccccc1

InChI Key InChIKey=LJJCYRVBDASIDX-DEOSSOPVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 144277   

TargetProtein-arginine deiminase type-6(Homo sapiens (Human))
The Penn State Research Foundation

US Patent
LigandPNGBDBM144277(US8969333, YW3-56)
Affinity DataIC50:  3.50E+3nMT: 2°CAssay Description:The inhibition efficacy of PAD4 inhibitors were determined by colorimetric measurement of citrulline generated by PAD4 catalyzed citrullination of BA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein-arginine deiminase type-4(Homo sapiens (Human))
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM144277(US8969333, YW3-56)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PAD4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM144277(US8969333, YW3-56)
Affinity DataIC50:  98nMAssay Description:Inhibition of recombinant human PDE4 using histone H3 as substrate by ELISA-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zhejiang Ocean University

Curated by ChEMBL
LigandPNGBDBM144277(US8969333, YW3-56)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of PDE4 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed