BDBM144279 US8969333, CI-amidine

SMILES NC(=O)[C@H](CCCNC(=N)CCl)NC(=O)c1ccccc1

InChI Key InChIKey=BPWATVWOHQZVRP-NSHDSACASA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144279   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zhejiang Ocean University

Curated by ChEMBL

LigandBDBM144279(US8969333, CI-amidine)Copy SMILESCopy InChI

Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of PDE4 (unknown origin) by colorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProtein-arginine deiminase type-6(Homo sapiens (Human))
The Penn State Research Foundation

US Patent

LigandBDBM144279(US8969333, CI-amidine)Copy SMILESCopy InChI

Affinity DataIC50:  1.25E+4nMT: 2°CAssay Description:The inhibition efficacy of PAD4 inhibitors were determined by colorimetric measurement of citrulline generated by PAD4 catalyzed citrullination of BA...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI