BDBM144504 US8969568, 103::US8969568, 104::US8969568, 105::US8969568, 106::US8969568, 109::US8969568, 110::US8969568, 114::US8969568, 116::US8969568, 57

SMILES Cc1cc2ncccc2c(OC[C@H]2CNC(=O)C2)n1

InChI Key InChIKey=LGLTUBADVDGOPY-SNVBAGLBSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 144504   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  13.7nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  4.70nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  2.10nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  5.10nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  7.40nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  20.4nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  4.70nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  17.8nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144504(US8969568, 103 | US8969568, 104 | US8969568, 105 |...)
Affinity DataIC50:  6.20nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent