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BDBM145302 US8952169, 81

SMILES: CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2(CCC2)C(F)(F)F)cc1F

InChI Key: InChIKey=WRVKFPOKTBLSJR-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145302   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145302
PNG
(US8952169, 81)
Show SMILES CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2(CCC2)C(F)(F)F)cc1F
Show InChI InChI=1S/C14H14ClF4NO4S/c1-25(22,23)20-12(21)8-5-9(15)11(6-10(8)16)24-7-13(3-2-4-13)14(17,18)19/h5-6H,2-4,7H2,1H3,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 122n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc.; Genentech, Inc.

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair