BDBM145693 US8952177, 47::US9089569, 47::US9695149, 47

SMILES Cn1ccc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4ccc(cc4)C#N)c3c2)n1

InChI Key InChIKey=XLLATHNCWICDAZ-PKTZIBPZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 145693   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM145693(US8952177, 47 | US9089569, 47 | US9695149, 47)
Affinity DataKi:  490nMAssay Description:FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM145693(US8952177, 47 | US9089569, 47 | US9695149, 47)
Affinity DataKi:  490nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM145693(US8952177, 47 | US9089569, 47 | US9695149, 47)
Affinity DataKi:  490nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails US Patent