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BDBM145855 US8956589, 27

SMILES: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(c2)C(F)(F)F)ccc1O

InChI Key: InChIKey=ZVURMUCQBPLFJF-YPCIICBESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145855   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta amyloid A4 protein


(Homo sapiens (human))
BDBM145855
PNG
(US8956589, 27)
Show SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(c2)C(F)(F)F)ccc1O
Show InChI InChI=1S/C21H17F3O5/c1-29-20-11-14(5-9-19(20)28)3-7-16(26)12-15(25)6-2-13-4-8-18(27)17(10-13)21(22,23)24/h2-11,27-28H,12H2,1H3/b6-2+,7-3+
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 130n/an/an/an/a7.530



Shiga University of Medical Science

US Patent


Assay Description
First, amyloid beta peptides (1-40, Peptide Institute, Minoh-shi, Osaka) were dissolved in a 50 mM phosphate buffer containing 100 mM sodium chloride...


US Patent US8956589 (2015)


BindingDB Entry DOI: 10.7270/Q2BG2MQ5
More data for this
Ligand-Target Pair