BDBM148427 US9682963, 15

SMILES Cc1cc(NC2CCOC2=O)ccc1NC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1F

InChI Key InChIKey=LDZNWBJMELLLOX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 148427   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Redx Pharma

US Patent
LigandPNGBDBM148427(US9682963, 15)
Affinity DataIC50: <100nMpH: 7.5 T: 2°CAssay Description:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO. Required cofactor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent