BDBM149487 US8975261, I-31

SMILES COc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1C1=CCC(O)CC1

InChI Key InChIKey=XZMMWKAYVRDZIF-AGPBCMBSSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149487   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM149487(US8975261, I-31)
Affinity DataKi:  0.150nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds of the present invention was determined in accordance with the following exper...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent