BDBM149701 US8975282, 8

SMILES Cc1c(C(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cn2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=UMMZZOSIEGYDTO-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 149701   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM149701(US8975282, 8)
Affinity DataKd:  2.40nMpH: 7.0 T: 2°CAssay Description:Met (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 .mu.M KKKSPGEYVNIEFG, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activity appr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM149701(US8975282, 8)
Affinity DataKd:  3.20nMpH: 7.0 T: 2°CAssay Description:KDR (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM MgAcetate and [.gamma.-.sup.33P-ATP] (specific activi...More data for this Ligand-Target Pair
In DepthDetails US Patent