BDBM151875 US8987457, 69

SMILES CO[C@@H]1[C@@H](C)C[C@H](C[C@H]1N)c1ccncc1NC(=O)c1nc(sc1N)-c1c(F)cccc1F

InChI Key InChIKey=JNOBBFHKVJLMIK-CGVCYLSUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 151875   

TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM151875(US8987457, 69)
Affinity DataIC50:  0.400nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM151875(US8987457, 69)
Affinity DataIC50:  1.17nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM151875(US8987457, 69)
Affinity DataIC50:  0.0400nMAssay Description:Pim 1, Pim 2 & Pim 3 AlphaScreen assays using high ATP (11-125.times. ATP Km) were used to determine the biochemical activity of the inhibitors. The ...More data for this Ligand-Target Pair
In DepthDetails US Patent