BDBM152211 BDBM152229::US8993552, 1
SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12
InChI Key InChIKey=MNSXQGKLDTVOLP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 152211
Affinity DataIC50: 1.90E+3nMAssay Description:Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...More data for this Ligand-Target Pair