BDBM152676 US10023561, Example 91::US9682965, 91

SMILES [#6]-[#8]-[#6@@H]-1-[#6@@H](-[#6]-[#6][C@]2([#6]-[#8]2)[#6@H]-1[C@@]1([#6])[#8]-[#6@@H]1-[#6]\[#6]=[#6](\[#6])-[#6])-[#8]-[#6](=O)-[#7]-1-[#6]-[#6](-[#6]-[#6]-[#6]-2-[#6]-[#6]-[#7](-[#6]-[#6](F)F)-[#6]-[#6]-2)-[#6]-1

InChI Key InChIKey=WMMOZHHRCIIDJE-UFRBKFNPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152676   

TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Zafgen

US Patent
LigandPNGBDBM152676(US10023561, Example 91 | US9682965, 91)
Affinity DataIC50:  275nMpH: 7.4Assay Description:The plate was sealed with a TopSeal A cover and mixed briefly on an orbital mixer at 900 rpm. The plate was incubated for a further 25 minutes at 25Â...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMethionine aminopeptidase 2(Homo sapiens (Human))
Zafgen

US Patent
LigandPNGBDBM152676(US10023561, Example 91 | US9682965, 91)
Affinity DataIC50:  275nMpH: 7.4Assay Description:Flag tagged Human recombinant MetAP2 expressed and isolated for use as the enzyme source. 10 mM stock solutions of compounds were prepared in 100% DM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent