BDBM15319 6-{4-[(2-benzyl-3-oxocyclohex-1-en-1-yl)amino]-3-fluorophenyl}-5-methyl-2,3,4,5-tetrahydropyridazin-3-one::dihydropyridazinone 14m
SMILES CC1CC(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3)C(=O)CCC2)c(F)c1
InChI Key InChIKey=VBWJKVQHSONPKM-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 15319
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112](Homo sapiens (Human))
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 1.20nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Homo sapiens (Human))
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 0.260nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair