BDBM153222 US8993756, 20-3

SMILES CC(=C)C(=O)Nc1cccc(c1)-c1ncnc2[nH]cc(-c3ccccc3F)c12

InChI Key InChIKey=DJQYUNLSKBBFMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153222   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153222(US8993756, 20-3)
Affinity DataIC50: >1.50E+3nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM153222(US8993756, 20-3)
Affinity DataIC50:  0.960nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAKl, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent