BDBM153481 US8999955, 5-hydroxy-8-methoxy-1-trimethylsilanyl-3,3a,4,5-tetrahydro-2H-cyclopenta[c]acridin-2-one

SMILES COc1ccc2nc3C4=C(C(=O)CC4CC(O)c3cc2c1)[Si](C)(C)C

InChI Key InChIKey=GPLFVGIGKBFDJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153481   

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153481(US8999955, 5-hydroxy-8-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  4.00E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM153481(US8999955, 5-hydroxy-8-methoxy-1-trimethylsilanyl-...)
Affinity DataIC50:  1.70E+3nMAssay Description:The tests are carried out as follows: the enzyme to be assayed was purified, for example by affinity chromatography on agarose beads. The catalytic a...More data for this Ligand-Target Pair
In DepthDetails US Patent