BDBM15412 5-[4-(4-Fluoro-phenyl)-oxazol-5-yl]-1-isopropyl-3-methyl-1,3-dihydrobenzoimidazol-2-one::5-[4-(4-fluorophenyl)-1,3-oxazol-5-yl]-3-methyl-1-(propan-2-yl)-2,3-dihydro-1H-1,3-benzodiazol-2-one::Benzimidazolone deriv. 15

SMILES CC(C)n1c2ccc(cc2n(C)c1=O)-c1ocnc1-c1ccc(F)cc1

InChI Key InChIKey=OXLPMUKQYFIPBW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15412   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15412(5-[4-(4-Fluoro-phenyl)-oxazol-5-yl]-1-isopropyl-3-...)
Affinity DataIC50:  30nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed