BindingDB PrimarySearch

BDBM15581 CHEMBL8706::CLG::CLORGILINE::Clorgyline::N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine::US8633208, Clorgyline::[3-(2,4-dichlorophenoxy)propyl](methyl)prop-2-yn-1-ylamine

SMILES: CN(CCCOc1ccc(Cl)cc1Cl)CC#C

InChI Key: InChIKey=BTFHLQRNAMSNLC-UHFFFAOYSA-N

Data: 14 KI 102 IC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 116 hits for monomerid = 15581
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma (HUMAN)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical College of Georgia Curated by PDSP K_i Database									Citation and Details
Medical College of Georgia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A) (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	-10.3	n/a	n/a	n/a	n/a	n/a	7.4	38
Universita di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007)
Universita di Roma La Sapienza					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase A in isolated bovine brain mitochondria				J Med Chem 46: 917-20 (2003)
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008)
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOA using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...				J Med Chem 55: 10424-36 (2012)
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turku Curated by PDSP K_i Database									Citation and Details
University of Turku Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Turku Curated by PDSP K_i Database									Citation and Details
University of Turku Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009)
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 2B1 (Rattus norvegicus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Mechanism based inhibition of rat cytochrome P450 CYP2B1 measured by 7-EFC O-deethylation activity				Citation and Details
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burk plot				Bioorg Med Chem 17: 675-89 (2009)
Hacettepe University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Roma La Sapienza					Assay Description MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...				J Med Chem 50: 922-31 (2007)
Universita di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Università di Roma Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay				Bioorg Med Chem 16: 9729-40 (2008)
Sapienza Università di Roma Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibitory activity against monoamine oxidase B in isolated bovine brain mitochondria				J Med Chem 46: 917-20 (2003)
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Inhibition of bovine brain MAOB using kinuramine as substrate preincubated for 30 mins prior to substrate addition measured after 30 mins by fluorome...				J Med Chem 55: 10424-36 (2012)
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	7.4	37
Universita degli Studi di Roma La Sapienza					Assay Description The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...				J Med Chem 52: 2818-24 (2009)
Universita degli Studi di Roma La Sapienza					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Rottapharm S.p.A US Patent					Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...				Citation and Details
Rottapharm S.p.A US Patent					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rottapharm S.p.A US Patent					Assay Description Inhibitory activity of compounds was evaluated by a homogeneous luminescent method, the MAO-Glo Assay (Promega), measuring the monoamine oxidase acti...				Citation and Details
Rottapharm S.p.A US Patent					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017)
Quaid-i-Azam University					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017)
Quaid-i-Azam University					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University					Assay Description Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...				Bioorg Chem 71: 305-314 (2017)
Sichuan University					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University					Assay Description Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...				Bioorg Chem 71: 305-314 (2017)
Sichuan University					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Roma La Sapienza P.le Aldo Moro Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BT1 cells				Bioorg Med Chem Lett 20: 6479-82 (2010)
					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Roma La Sapienza P.le Aldo Moro Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BT1 cells				Bioorg Med Chem Lett 20: 6479-82 (2010)
					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...				Bioorg Med Chem 22: 2887-95 (2014)
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cell microsomes assessed as decrease in H2O2 production using p-...				Bioorg Med Chem 22: 2887-95 (2014)
Sapienza University of Rome Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver homogenate using [14C]-5HT as substrate preincubated for 30 mins followed by substrate addition measured after 20 mi...				Eur J Med Chem 80: 543-61 (2014)
Okayama University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver homogenate using [14C]-phenylethylamine as substrate preincubated for 30 mins followed by substrate addition measure...				Eur J Med Chem 80: 543-61 (2014)
Okayama University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anhui Medical University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using p-tyramine as substrate assessed as production of H2O2 incubated for 15 mins prior to substrate addition ...				Bioorg Med Chem 23: 515-25 (2015)
Anhui Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Dart NeuroScience, LLC Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat whole brain homogenate in presence of clorgyline				Bioorg Med Chem 23: 770-8 (2015)
Dart NeuroScience, LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Qu�mica M�dica, (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of human MAO-B expressed in baculovirus infected BTI insect cells preincubated for 15 mins				J Med Chem 57: 10455-63 (2014)
					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Qu�mica M�dica, (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells preincubated for 15 mins				J Med Chem 57: 10455-63 (2014)
					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain MAO-A preincubated for 60 mins before substrate addition by fluorimetric method				Eur J Med Chem 93: 308-20 (2015)
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain MAO-B preincubated for 60 mins before substrate addition by fluorimetric method				Eur J Med Chem 93: 308-20 (2015)
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Assiut University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-B by spectrofluorimetry				Eur J Med Chem 93: 481-91 (2015)
Assiut University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Assiut University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-A by spectrofluorimetry				Eur J Med Chem 93: 481-91 (2015)
Assiut University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase B (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of MAO-B in bovine brain mitochondria using benzylamine as substrate				Bioorg Med Chem Lett 25: 70-4 (2015)
King Saud University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
King Saud University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using serotonin as substrate preincubated with enzyme for 60 mins prior to substrate addition				Bioorg Med Chem Lett 25: 70-4 (2015)
King Saud University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using kynuramine substrate by spectrophotometric assay				J Med Chem 58: 5561-78 (2015)
					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using kynuramine substrate by spectrophotometric assay				J Med Chem 58: 5561-78 (2015)
					More data for this Ligand-Target Pair
Monoamine oxidase B (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-B using benzylamine substrate after 60 mins by fluorimetric method				Bioorg Med Chem 23: 3574-85 (2015)
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase A (Bos taurus)	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Alexandria University Curated by ChEMBL					Assay Description Inhibition of bovine brain mitochondria MAO-A using serotonin substrate after 60 mins by fluorimetric method				Bioorg Med Chem 23: 3574-85 (2015)
Alexandria University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using p-tyramine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluor...				Bioorg Med Chem 23: 3722-9 (2015)
					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Jena Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB				Citation and Details
University of Jena Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Jena Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				Citation and Details
University of Jena Curated by ChEMBL					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate after 30 mins by Amplex red based spectrophotometric analysis				Citation and Details
					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOB using benzylamine as substrate after 30 mins by Amplex red based spectrophotometric analysis				Citation and Details
					More data for this Ligand-Target Pair
Monoamine oxidase type B (MAO-B) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB				J Med Chem 51: 4874-80 (2008)
					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOA				J Med Chem 51: 4874-80 (2008)
					More data for this Ligand-Target Pair
Monoamine oxidase type A (MAO-A) (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hefei University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOA using p-tyramine as substrate assessed as H2O2 production preincubated for 15 mins followed by substrate additio...				Citation and Details
Hefei University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair

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