BDBM156234 US9018255, L-3a

SMILES CCOC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)C(=C)COC(=O)c1c(cccc1C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PIBIRGYHHYAZIQ-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156234   

TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156234(US9018255, L-3a)
Affinity DataIC50:  2.80E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent