BDBM15781 3-N-benzylpyridine-2,3-diamine::3-Substituted 2-Aminopyridine 5::aminopyridine 3::fragment 3 (J. med. chem.,50,1116)

SMILES Nc1ncccc1NCc1ccccc1

InChI Key InChIKey=MUKAGFLFIMVSQN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15781   

TargetBeta-secretase 1(Human)
Astex

LigandPNGBDBM15781(3-N-benzylpyridine-2,3-diamine | 3-Substituted 2-A...)
Affinity DataIC50:  3.10E+5nMpH: 5.0 T: 22°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Human)
Astex

LigandPNGBDBM15781(3-N-benzylpyridine-2,3-diamine | 3-Substituted 2-A...)
Affinity DataIC50:  3.10E+5nMpH: 5.0 T: 22°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair