BDBM15782 3-N-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine::3-Substituted 2-Aminopyridine 6a

SMILES Nc1ncccc1NCc1cccc(c1)-c1cccnc1

InChI Key InChIKey=NQSBHBFOOVYRNM-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15782   

TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM15782(3-N-{[3-(pyridin-3-yl)phenyl]methyl}pyridine-2,3-d...)
Affinity DataIC50:  1.00E+5nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair