BDBM15787 3-N-{[5-(1H-indol-6-yl)-2-(pyridin-2-ylmethoxy)phenyl]methyl}pyridine-2,3-diamine::3-Substituted 2-Aminopyridine 8b

SMILES Nc1ncccc1NCc1cc(ccc1OCc1ccccn1)-c1ccc2cc[nH]c2c1

InChI Key InChIKey=KMBPJSHPAXOXBT-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15787   

TargetBeta-secretase 1(Homo sapiens (Human))
Astex

LigandPNGBDBM15787(3-N-{[5-(1H-indol-6-yl)-2-(pyridin-2-ylmethoxy)phe...)
Affinity DataIC50:  4.20E+3nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair