BDBM159242 US9034866, 719

SMILES CN1CC[C@@](O)(C#Cc2ccc3OCC(F)(F)c4c(Cl)c(nn4-c3c2)C(N)=O)C1=O

InChI Key InChIKey=PYFYHVLWNLAZHP-SFHVURJKSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159242   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM159242(US9034866, 719)
Affinity DataKi:  0.400nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent