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BDBM159289 US9682968, Example-5-12

SMILES: Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)-c1nn[nH]n1

InChI Key: InChIKey=QJAJIJDEGTUFEF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159289   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159289
PNG
(US9682968, Example-5-12)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)-c1nn[nH]n1
Show InChI InChI=1S/C23H26N6/c1-15-13-16(2)22-19(10-11-24-22)20(15)14-29-12-4-3-5-21(29)17-6-8-18(9-7-17)23-25-27-28-26-23/h6-11,13,21,24H,3-5,12,14H2,1-2H3,(H,25,26,27,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0400n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair