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BDBM159301 US9682968, Example-11

SMILES: Cc1cc(C)c2[nH]ccc2c1CN1CCC(O)CC1c1ccc(cc1)C(N)=O

InChI Key: InChIKey=KGWKKJNMHAXSDP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159301   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159301
PNG
(US9682968, Example-11)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCC(O)CC1c1ccc(cc1)C(N)=O
Show InChI InChI=1S/C23H27N3O2/c1-14-11-15(2)22-19(7-9-25-22)20(14)13-26-10-8-18(27)12-21(26)16-3-5-17(6-4-16)23(24)28/h3-7,9,11,18,21,25,27H,8,10,12-13H2,1-2H3,(H2,24,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.230n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair