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BDBM159316 US9682968, Example-17-4

SMILES: COc1cc(ccc1[C@@H]1CCCCN1Cc1c(cc(C)c2[nH]ccc12)C1CC1)C(O)=O

InChI Key: InChIKey=UCDGYFITIWQJJE-QHCPKHFHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159316
PNG
(US9682968, Example-17-4)
Show SMILES COc1cc(ccc1[C@@H]1CCCCN1Cc1c(cc(C)c2[nH]ccc12)C1CC1)C(O)=O
Show InChI InChI=1S/C26H30N2O3/c1-16-13-21(17-6-7-17)22(19-10-11-27-25(16)19)15-28-12-4-3-5-23(28)20-9-8-18(26(29)30)14-24(20)31-2/h8-11,13-14,17,23,27H,3-7,12,15H2,1-2H3,(H,29,30)/t23-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0900n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair