BindingDB logo
myBDB logout

BDBM159382 US9682968, Example-17-10

SMILES: COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cn1)C(O)=O

InChI Key: InChIKey=PDQZVULLRBJFBQ-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159382
PNG
(US9682968, Example-17-10)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cn1)C(O)=O
Show InChI InChI=1S/C22H25N3O3/c1-14-11-20(28-2)17(16-8-9-23-21(14)16)13-25-10-4-3-5-19(25)18-7-6-15(12-24-18)22(26)27/h6-9,11-12,19,23H,3-5,10,13H2,1-2H3,(H,26,27)/t19-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.100n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair