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BDBM159486 US9682968, Example-17-11

SMILES: CCCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=PTJDUBVSNSKDOU-REWPJTCUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159486   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159486
PNG
(US9682968, Example-17-11)
Show SMILES CCCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C26H32N2O4/c1-4-13-32-20-10-12-28(23(15-20)18-5-7-19(8-6-18)26(29)30)16-22-21-9-11-27-25(21)17(2)14-24(22)31-3/h5-9,11,14,20,23,27H,4,10,12-13,15-16H2,1-3H3,(H,29,30)/t20-,23-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0200n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair