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BDBM159566 US9682968, Example-17-18

SMILES: COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(nc1)C(O)=O

InChI Key: InChIKey=LLFJQBNRYWKMTC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159566
PNG
(US9682968, Example-17-18)
Show SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(nc1)C(O)=O
Show InChI InChI=1S/C25H29N3O3/c1-15-11-20(16-3-4-16)21(19-7-9-26-24(15)19)14-28-10-8-18(31-2)12-23(28)17-5-6-22(25(29)30)27-13-17/h5-7,9,11,13,16,18,23,26H,3-4,8,10,12,14H2,1-2H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair