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BDBM159616 US9035059, 6-18

SMILES: CCCCCCCc1ccc(NS(=O)(=O)c2ccc3CN(CCc4ccc(cc4)C(C)(C)C)CCc3c2)c(F)c1

InChI Key: InChIKey=SLPXPEHGGKZYFG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159616   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159616
PNG
(US9035059, 6-18)
Show SMILES CCCCCCCc1ccc(NS(=O)(=O)c2ccc3CN(CCc4ccc(cc4)C(C)(C)C)CCc3c2)c(F)c1
Show InChI InChI=1S/C34H45FN2O2S/c1-5-6-7-8-9-10-27-13-18-33(32(35)23-27)36-40(38,39)31-17-14-29-25-37(22-20-28(29)24-31)21-19-26-11-15-30(16-12-26)34(2,3)4/h11-18,23-24,36H,5-10,19-22,25H2,1-4H3
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 35n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair