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BDBM159701 US9035059, 17-5

SMILES: CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCCCCc3ccccc3)cc2F)cc1

InChI Key: InChIKey=WGHOMSNLXIJGGH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159701   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159701
PNG
(US9035059, 17-5)
Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCCCCc3ccccc3)cc2F)cc1
Show InChI InChI=1S/C38H45FN2O3S/c1-38(2,3)33-16-13-30(14-17-33)21-23-41-24-22-31-26-35(19-15-32(31)28-41)45(42,43)40-37-20-18-34(27-36(37)39)44-25-9-5-8-12-29-10-6-4-7-11-29/h4,6-7,10-11,13-20,26-27,40H,5,8-9,12,21-25,28H2,1-3H3
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 24n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair