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BDBM159727 US9035059, 19-8

SMILES: CCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1

InChI Key: InChIKey=CHAOTVVTPXLQLB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 159727   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159727
PNG
(US9035059, 19-8)
Show SMILES CCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1
Show InChI InChI=1S/C32H40FN3O4S/c1-5-6-7-8-9-18-40-27-15-17-30(29(33)20-27)35-41(38,39)28-16-10-23-21-36(22-24(23)19-28)31(37)34-26-13-11-25(12-14-26)32(2,3)4/h10-17,19-20,35H,5-9,18,21-22H2,1-4H3,(H,34,37)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 28n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair