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BDBM159734 US9035059, 23-1::US9035059, 24-1/24-2

SMILES: CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C

InChI Key: InChIKey=DUVASYYCXRCGHW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 159734   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159734
PNG
(US9035059, 23-1 | US9035059, 24-1/24-2)
Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C
Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 13n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159734
PNG
(US9035059, 23-1 | US9035059, 24-1/24-2)
Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C
Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 29n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair
Acyl-CoA:monoacylglycerol acyltransferase 2 (MOGAT2)


(Homo sapiens (Human))
BDBM159734
PNG
(US9035059, 23-1 | US9035059, 24-1/24-2)
Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C
Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4n/an/an/an/an/an/a



TAISHO PHARMACEUTICAL CO., LTD.

US Patent


Assay Description
An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...


US Patent US9035059 (2015)

More data for this
Ligand-Target Pair