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BDBM159840 US10093663, Example 17-21::US9682968, Example-17-21

SMILES: Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1cccc(c1)C(O)=O

InChI Key: InChIKey=IDAQIBNNEOTNPN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159840   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM159840
PNG
(US10093663, Example 17-21 | US9682968, Example-17-...)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1cccc(c1)C(O)=O
Show InChI InChI=1S/C23H26N2O2/c1-15-12-16(2)22-19(9-10-24-22)20(15)14-25-11-4-3-8-21(25)17-6-5-7-18(13-17)23(26)27/h5-7,9-10,12-13,21,24H,3-4,8,11,14H2,1-2H3,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.840n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159840
PNG
(US10093663, Example 17-21 | US9682968, Example-17-...)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1cccc(c1)C(O)=O
Show InChI InChI=1S/C23H26N2O2/c1-15-12-16(2)22-19(9-10-24-22)20(15)14-25-11-4-3-8-21(25)17-6-5-7-18(13-17)23(26)27/h5-7,9-10,12-13,21,24H,3-4,8,11,14H2,1-2H3,(H,26,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 840n/an/an/an/a7.425



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US10093663 (2018)

More data for this
Ligand-Target Pair