BDBM16012 2-({5-fluoro-2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzoic acid::4-anilinopyrimidine 14b

SMILES OC(=O)c1ccccc1Nc1nc(Nc2cccc(O)c2)ncc1F

InChI Key InChIKey=UMIUXVPQKJLPJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16012   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM16012(2-({5-fluoro-2-[(3-hydroxyphenyl)amino]pyrimidin-4...)
Affinity DataIC50:  21nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed