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BDBM160177 US9040663, 23

SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(c2)[N+]([O-])=O)NC(=O)[C@H](CCN)NC1=O)C(N)=O

InChI Key: InChIKey=NHUZUKPPUDYEIX-IQSCWYJSSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160177   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM160177
PNG
(US9040663, 23)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2cccc(c2)[N+]([O-])=O)NC(=O)[C@H](CCN)NC1=O)C(N)=O
Show InChI InChI=1S/C48H70N18O11/c1-26(67)59-33(13-6-20-56-47(51)52)41(70)62-35-15-16-39(68)55-19-5-12-32(40(50)69)60-46(75)38(24-28-25-58-31-11-3-2-10-30(28)31)65-42(71)34(14-7-21-57-48(53)54)61-45(74)37(23-27-8-4-9-29(22-27)66(76)77)64-44(73)36(17-18-49)63-43(35)72/h2-4,8-11,22,25,32-38,58H,5-7,12-21,23-24,49H2,1H3,(H2,50,69)(H,55,68)(H,59,67)(H,60,75)(H,61,74)(H,62,70)(H,63,72)(H,64,73)(H,65,71)(H4,51,52,56)(H4,53,54,57)/t32-,33-,34-,35-,36-,37+,38-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

0.700 -13.0n/an/an/an/an/a7.537



AstraZeneca AB

US Patent


Assay Description
A competitive inhibition binding assay was performed for exemplified peptides according to the invention using membrane homogenates prepared from HEK...


US Patent US9040663 (2015)


BindingDB Entry DOI: 10.7270/Q29885SK
More data for this
Ligand-Target Pair