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BDBM160272 US9682968, Example-22-2b (-)

SMILES: COc1cc(C)c2[nH]ccc2c1CN1CCC(C)(C)CC1c1ccc(cc1)C(O)=O

InChI Key: InChIKey=BJJYQBOFWNDASV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM160272
PNG
(US9682968, Example-22-2b (-))
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC(C)(C)CC1c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C25H30N2O3/c1-16-13-22(30-4)20(19-9-11-26-23(16)19)15-27-12-10-25(2,3)14-21(27)17-5-7-18(8-6-17)24(28)29/h5-9,11,13,21,26H,10,12,14-15H2,1-4H3,(H,28,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.0100n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair