BDBM1604 1 1 -C yclopropyl-5,ll -dihydro-4- [ (2-hydroxyphenyl)methyl]-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepind-6-one::2-cyclopropyl-7-[(2-hydroxyphenyl)methyl]-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one::Nevirapin 4-substituted deriv. 4aa
SMILES Oc1ccccc1Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12
InChI Key InChIKey=SNEUVPRZHPSNON-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1604
TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Pharmaceuticals
Affinity DataIC50: 190nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair