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BDBM160484 US9682968, Example-27-3b (+)

SMILES: COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=CKPFEBYAYLCXDR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160484   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM160484
PNG
(US9682968, Example-27-3b (+))
Show SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C26H30N2O3/c1-16-13-22(17-3-4-17)23(21-9-11-27-25(16)21)15-28-12-10-20(31-2)14-24(28)18-5-7-19(8-6-18)26(29)30/h5-9,11,13,17,20,24,27H,3-4,10,12,14-15H2,1-2H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 0.740n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair