BDBM160525 US10280160, Example 22.::US9682969, 17::US9682969, 22
SMILES CCOc1ccc2c(nn(CC(=O)N(C)c3ccc4nc(C)oc4c3)c(=O)c2c1)-c1cccc(F)c1
InChI Key InChIKey=XRPSUWYWZUQALB-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 160525
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Human)
Flatley Discovery Lab
US Patent
Flatley Discovery Lab
US Patent
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...More data for this Ligand-Target Pair
Affinity DataEC50: <1.00E+4nMAssay Description:Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Human)
Flatley Discovery Lab
US Patent
Flatley Discovery Lab
US Patent
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair