BDBM160525 US10280160, Example 22.::US9682969, 17::US9682969, 22

SMILES CCOc1ccc2c(nn(CC(=O)N(C)c3ccc4nc(C)oc4c3)c(=O)c2c1)-c1cccc(F)c1

InChI Key InChIKey=XRPSUWYWZUQALB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 160525   

TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Flatley Discovery Lab

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)
Affinity DataEC50: <1.00E+4nMAssay Description:Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Flatley Discovery Lab

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)
Affinity DataEC50: <1.00E+4nMAssay Description:Fisher Rat Thyroid (FRT) cells stably expressing both human F508del CFTR and a halide-sensitive yellow fluorescent protein (YFP-H148Q/I152L 25,22) (G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
In DepthDetails US Patent