BDBM161240 US10087143, Compound 25::US9051270, 25

SMILES FC(F)(F)c1ccc(Oc2ccc(cc2)[N+]#[C-])c(c1)C(=O)Nc1cc[nH]c(=O)c1

InChI Key InChIKey=BSRMCFBLDHOFPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161240   

TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161240(US10087143, Compound 25 | US9051270, 25)
Affinity DataIC50:  1.10E+3nMAssay Description:Sodium channels are voltage-dependent proteins that can be activated by inducing membrane voltage changes by applying electric fields. The electrical...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Rattus norvegicus (Rat))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM161240(US10087143, Compound 25 | US9051270, 25)
Affinity DataIC50:  1.10E+3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In DepthDetails US Patent