BDBM161600 US9108983, Example 417

SMILES COc1ccc(-c2cc(C(=O)N(c3cc(C#N)n(C)c3C)c3ccc(O)cc3)c(C)n2C)c(c1)C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1

InChI Key InChIKey=HIMDTPSTDUWZRB-XIFFEERXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161600   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM161600(US9108983, Example 417)
Affinity DataIC50:  3nMpH: 7.4Assay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
In DepthDetails US Patent